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KMID : 1039420170510030320
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Journal of Pathology and Translational Medicine
2017 Volume.51 No. 3 p.320 ~ p.324
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Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report
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Lee Hye-Kyung
Kang Dong-Wook
Kim Hee-Jin
Cho Byung-Sun
Jang Je-Ho
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Abstract
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Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.
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KEYWORD
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Eosinophils, Ganglionitis, Pseudo-obstruction
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